If you’re looking to refresh your skin without going down the filler route, you’ve probably heard of Profhilo and Polynucleotides.

Both are brilliant non-surgical options we offer at Dr Louise Pierre Aesthetics, and both fall under the exciting category of biostimulators — treatments that help your skin heal, hydrate and rejuvenate itself.

But how do you know which one is right for you? Let’s explore the differences in a simple, no-jargon way.

Rather than adding volume (like traditional fillers do), biostimulators work with your skin, encouraging it to regenerate and produce more of what it naturally needs — think collagen, elastin and hydration.

In other words, they wake your skin up and get it working better from within.

If your skin is feeling dull, tired or just not as bouncy as it used to be, Profhilo might be exactly what you need.

• It’s packed with pure hyaluronic acid (the same substance your body naturally produces to keep skin plump and hydrated).
• Once injected, it spreads evenly under the skin, giving you a gorgeous, natural glow.
• It also boosts collagen and elastin, improving firmness over time.

Perfect for:

✔ Dry or crepey skin
✔ Fine lines
✔ Skin that needs a bit of a “drink”

Treatment plan: Two sessions, four weeks apart – that’s it!

Polynucleotides are the latest buzz in regenerative aesthetics – and for good reason. They’re derived from salmon DNA (yes, really!) and are packed with molecules that kickstart repair and calm inflammation.

They help to rebuild damaged skin, reduce redness, improve texture, and even work wonders under the eyes.

Think of them as a deep reset button for your skin.

Perfect for:

✔ Sensitive or inflamed skin
✔ Acne scars
✔ Tired under-eyes
✔ Overall skin strengthening

Treatment plan: Usually a course of 3–4 sessions.

Absolutely, In fact, we often recommend a combined approach.

Profhilo gives you that immediate hydration and glow, while Polynucleotides work quietly behind the scenes to repair and future-proof your skin.

It’s not one vs. the other — it’s about choosing the right tool (or mix of tools) for your unique skin.

At Dr. Louise Pierre Aesthetics, located in Peacehaven and Streatham, the team offers expert polynucleotide injectable treatments for those seeking healthier, more youthful-looking skin. Dr. Louise Pierre’s approach focuses on delivering natural results, so you can enhance your beauty without drastic changes. With a personalized consultation, the clinic helps you determine the best treatment plan for your needs.

Patients are initially invited for a consultation and facial assessment. This allows Dr Louise to go through exactly what you desire from the treatment, what results can be expected from the treatment, your suitability for the procedure, treatment costs and any further questions you may have.

Treatment itself is relatively quick and simple, but never rushed. Every patient is seen on an individual basis, with a bespoke treatment tailored to suit personal requirement.

To schedule a consultation with our resident Doctor today or to discuss anti wrinkle treatments further, use our form below or call us on  0800 970 4940.